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Dvyser offers molecular solutions specifically designed for clinical laboratories that require reliable results, simple protocols, and high performance. Below are its strategic lines by diagnostic area and the most representative products.

Genetics and Hereditary Diseases
Focus: robust and standardized genetic testing solutions for the diagnosis, screening, and monitoring of hereditary conditions.
Products by area:

 

Molecular Hematology

Focus: reliable detection of genetic alterations associated with hematologic diseases.

 

Key products:

• Devyser Factor V Leiden – Rapid identification of the G1691A mutation.
• Devyser Prothrombin (Factor II) – Detection of the G20210A variant.
• Devyser MTHFR – Analysis of the C677T and A1298C polymorphisms.
• Devyser Thalassemia NGS – Comprehensive testing for alpha and beta thalassemia.

 

Ideal for: thrombosis risk assessment, thalassemia testing, and clinical hematology.

 

Pharmacogenetics

Focus: analysis aimed at optimizing pharmacological treatment according to the patient’s genetic profile.

 

Key products:

• Devyser CYP450 Panel – Evaluation of key variants involved in drug metabolism.
• Devyser TPMT – Determination of metabolic status for thiopurine therapies.

 

Ideal for: oncology, psychiatry, immunosuppressive therapies, and personalized medicine.

 

Prenatal and Neonatal Diagnostics
Focus: solutions designed for highly sensitive genetic studies in prenatal and reproductive contexts.
Key products:

• Devyser Aneuploidy assays – Detection of common chromosomal alterations.
• Devyser Cystic Fibrosis – Expanded panel for mutations associated with cystic fibrosis.
• Devyser RHD – Non-invasive prenatal fetal RHD screening.
• Devyser AZF – Detection of Y-chromosome microdeletions associated with male infertility.

Ideal for: reproductive genetics laboratories, prenatal diagnostics, and neonatal screening.

 

Oncology
Focus: targeted genetic testing for the detection of clinically significant variants associated with hereditary cancer and personalized cancer care.
Key products:

• Devyser BRCA NGS – Detection of variants in BRCA1 and BRCA2 associated with hereditary breast and ovarian cancer.
• Devyser HBOC NGS – Targeted sequencing of 12 genes associated with hereditary breast and ovarian cancer.
• Devyser BRCA PALB2 NGS – Detection of variants in BRCA1, BRCA2, and PALB2 for germline and somatic analysis.
• Devyser LynchFAP – Detection of variants associated with hereditary colorectal cancer, including analysis of PMS2.

Ideal for: oncology laboratories, hereditary cancer testing, molecular diagnostics, and personalized medicine.

 

Cardiovascular Diseases
Focus: genetic testing for the identification of hereditary risk factors associated with cardiovascular diseases and thrombosis.
Key products:

• Devyser CVD – Detection of genetic risk factors associated with cardiovascular disease.
• Devyser Factor V Leiden – Detection of the G1691A mutation associated with thrombosis risk.
• Devyser Prothrombin (Factor II) – Detection of the G20210A variant.
• Devyser MTHFR – Analysis of the C677T and A1298C polymorphisms.

Ideal for: cardiovascular genetics, thrombosis risk assessment, clinical hematology, and familial risk screening.

 

Cystic Fibrosis
Focus: genetic testing solutions for the detection of CFTR mutations associated with cystic fibrosis.
Key products:

• Devyser CFTR NGS – Full CFTR gene sequencing for comprehensive mutation detection.
• Devyser CFTR 68 – Detection of 68 CFTR mutations, including the polyT tract and associated TG repeats.
• Devyser CFTR Core – Detection of common CFTR mutations.
• Devyser CFTR Italia – Targeted detection of CFTR mutations commonly found in the Italian population.

Ideal for: cystic fibrosis diagnosis, carrier screening, prenatal diagnostics, and neonatal screening.

 

Post-Transplantation Monitoring
Focus: sensitive molecular solutions for monitoring engraftment, detecting relapse, and assessing residual disease following transplantation.
Key products:

• Devyser Chimerism NGS – Measurement of donor/recipient chimerism for post-transplant monitoring.
• One Lambda™ Devyser Accept cfDNA – Detection of donor-derived cell-free DNA for monitoring following kidney transplantation.
• Devyser HLA Loss – NGS-based solution for HLA loss detection in post-transplant monitoring.

Ideal for: transplant laboratories, hematopoietic stem cell transplantation, kidney transplantation, and molecular monitoring.